Endocrine Abstracts

Introduction: Several familial disorders could be associated with adrenal pheochromocytoma such as Von Hippel–Lindau (VHL) syndrome, multiple endocrine neoplasia type 2 (MEN2) and, less commonly, neurofibromatosis type 1 (NF1). Herein, we report three cases of pheochromocytoma as a part of genetic syndromes.ObservationsPatient 1A 34-year-old women with no familial history, was diagnosed with severe hype...

Introduction: Clinical presentation of hypothyroidism is frequently insidious. Of the many non specific clinical signs of hypothyroidism, ascites is one of the less common manifestations reported and the diagnosis is often made late with this condition. Herein, we present the cases of isolated ascites revealing hypothyroidism in order to drow attention to hypothyroidism as an etiology of an unexplained isolated ascites.Observation: A 61-year-old diabetic...

Introduction: Thyroid ectopy is uncommon pathology. The lingual area is the most frequent localization. The medaistinal localization is rare. We report in this article two cases illustrating this location.1st clinical case66-year-old woman operated on for benign breast cysts consulted for progressive chest pain. The clinical examination was without abnormalities. The standard biological assessment was normal. Cervicothoracic CT sca...

Introduction: Autoimmune polyendocrine syndrome ( APS ) is a rare, inherited disorder, characterized by autoimmune thyroiditis with another organ specific autoimmune disease.ObservationWe report the case of 55 years old woman, descendant of a first degree consanguineous marriage, who presented at the age of 35 a premature ovarian insufficiency and alopecia. Eight months later, she developed a goiter with hyperthyroidism and the dia...

Diabetes in paraneoplastic Cushing is often severe with a risk of acute metabolic complications.Observation n° 1: A 36-year-old patient, with no medical history, was hospitalized for inaugural diabetic ketoacidosis with no intercurrent infection. The physical examination found facio-truncal obesity, amyotrophy of extremities, melanoderma, arterial hypertension and severe psychiatric disorders. The blood tests showed an hypokalemia at 1.9 mmol/l. Hig...

IntroductionPheochromocytomas are rare catecholamine-producing neuroendocrine tumors derived from the sympathetic or parasympathetic nervous system. The clinical presentation of pheocromocytoma has varying forms, which makes diagnosing it challenging. Here, we report a case of Adrenergic cardiomyopathy mimicking COVID-19.Case reportA 40-year-old woman with a history of pulmonary edema during cesarean delivery...

BackgroundHypoglycemia is a well-established as a serious paraneoplastic complication of hepatocellular carcinoma (HCC). However, hypoglycemia presenting the first presentation of HCC is not frequent. In this regard, we present the case of a patient who had hypoglycemia as first manifestation of HCC.ObservationA 55yearold man presented to the Emergency Department with loss of consciousness preceded by dizzine...

IntroductionInsulinoma is the most frequent pancreatic endocrine tumor and is confirmed in case of a hyperinsulinic hypoglycemia with elevated C-peptide and absence of sulfonylureas. Tomodensitometry, MRI, endoscopic ultrasound are the imaging means used to assess localization before surgery as it is not always determined by one mean only, and in a few cases, all means may not determine localization.MethodsTh...

IntroductionSpontaneous hypoglycemia in non-diabetic adults represent a challenge in confirming the organic cause, requiring in that case specific medication or surgery, in a setting of a possible life-threatening disease.MethodsWe conducted a retrospective study of patients admitted in our department for spontaneous hypoglycemia. Functional and factitious etiology were excluded. Clinical and biologic feature...

IntroductionThe empty sella syndrome is a rare disorder characterized by a flattened pituitary gland leaving place to the cerebrospinal fluid to fill in the sella turcica.The diagnosis is radiological and it is often discovered during pituitary disorders. Generally patients suffer from hypopituitarism, and primary hypothyroidism is found to be a rare association.ObservationHerein the case of a young woman who...